Where reason has lost its sway, argument has lost its value. You are no longer dealing with ideas and concepts but with emotions and feelings. It is impossible to argue with feelings and emotions, as they have no root in objective reality, but are a response to experiences, good and bad.
Transgenderism is a belief that is not upheld by science. A person claims to be transgender by identification, which is an mental or emotional attachment to an idea. The person who claims to be a female, but is in fact a male, is denying the scientific fact of biology, genetics and DNA. It is therefore a religious belief, whose enforcement by the state violates the First Amendment’s second clause by establishing a religion.